Can a AMD Radeon R9 390 run Deus Ex: Mankind Divided?

Yes — runs well

The AMD Radeon R9 390 handles Deus Ex: Mankind Divided comfortably — roughly 64 FPS at 1080p and 40 FPS at 1440p on high settings.

64FPS @ 1080p
40FPS @ 1440p
23FPS @ 4K

High preset, upscaling off, paired with a AMD Ryzen 7 9800X3D-class processor.

How the AMD Radeon R9 390 measures up

RequirementAMD Radeon R9 390MinimumRecommendedResult
GPU performance score 16 6 15 Recommended
Video memory 8 GB 2 GB 4 GB Recommended
Ray tracing — Not supported Game has no RT N/A
Upscaling FSR Not supported N/A

Recommended settings

For 60 FPS at 1080p

Use the high preset. You already clear 60 FPS on high, so this leaves headroom for dips in busy scenes.

At 1440p

Around 40 FPS on high. Playable, but drop to medium or enable upscaling for a stable 60.

At 4K

Around 23 FPS — not a realistic target for this pairing.

How other cards handle Deus Ex: Mankind Divided

Graphics cardTier1080p FPSvs AMD Radeon R9 390
AMD Radeon R9 390X D 64 ▼ 0 FPS Compare
AMD Radeon RX 5500 XT 8GB D 64 ▼ 0 FPS Compare
AMD Radeon RX 580 4GB D 64 ▼ 0 FPS Compare
AMD Radeon RX 480 8GB D 64 ▼ 0 FPS Compare
NVIDIA GeForce GTX 1650 SUPER D 60 ▼ 4 FPS Compare
NVIDIA GeForce GTX 1060 6GB D 60 ▼ 4 FPS Compare

Frequently asked questions

Can the AMD Radeon R9 390 run Deus Ex: Mankind Divided?

The AMD Radeon R9 390 handles Deus Ex: Mankind Divided comfortably — roughly 64 FPS at 1080p and 40 FPS at 1440p on high settings.

What FPS will I get?

On high settings with upscaling off: roughly 64 FPS at 1080p, 40 FPS at 1440p and 23 FPS at 4K. These are modelled estimates — see our methodology.

What settings should I use?

Start at the high preset at 1080p.

Will my processor hold this back?

These figures assume a processor fast enough not to limit the card. If yours is older, run the bottleneck calculator — this title leans on the GPU, so a modest CPU deficit costs less.